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Pablo Debenedetti
Faculty Fellow
Dean for Research. Class of 1950 Professor in Engineering and Applied Science. Professor of Chemical and Biological Engineering.


609-258-5480
91 Prospect Avenue
E-mail

Debenedetti Research Group

My research program investigates the relationship between molecular architecture and the structural, thermodynamic and kinetic properties of condensed matter systems of interest in modern chemical and biological engineering. We employ computational and theoretical methods rooted in statistical mechanics to study problems such as the effects of co-solutes, pressure and temperature on protein stability; the origin of biological homochirality; the structure, dynamics and phase behavior of water in nano-scale confinement; dynamics in supercooled liquids; the thermodynamics of supercooled water; drying and hydration of complex and biological substrates; the thermodynamics, formation mechanisms and formation kinetics of clathrate hydrates; desalintion via clathrate hydrates; and the properties of proteins and other biomolecules under low-moisture conditions and in glassy matrices.